Rheumatic fever—a vignette

Clinical Vignette Session A: Vignette Award Finalists

CASE: A 50-year-old female with chronic obstructive pulmonary disease, tobacco use and bipolar disorder presented with acute, intense substernal chest pain and heart rate of 170 bpm. She had no previous cardiac history and no similar episodes in the past. She started taking lithium 2 months earlier for bipolar disorder. Her electrocardiogram showed inferior ST depression and an incomplete left ...

Anaquin - Vignette

This vignette is written for R-usage. However, Anaquin is a framework covering the entire RNA-Seq workflow; reads alignment, transcriptome assembly, gene expression and differential analysis, etc. Consequently, the R-package (and it’s documentation) is a subset of the overall Anaquin framework. We also distribute a workflow guide with this vignette on how Anaquin can be integrated with a bioinf...

GiANT package vignette

mombf package vignette

This manual shows how to use the mombf library to compute Moment and inverse Moment Bayes factors (Mom BF and iMom BF, respectively). The intuitive appeal of Mom and iMom BF is that they represent prior beliefs under the alternative hypothesis which are fundamentally different from those under the null hypothesis. Mathematically, when the null hypothesis is true they present better convergence ...

CMA package vignette

Moreover, model selection and evaluation of prediction rules proves to be highly difficult in this situation for several reasons. Firstly, the hazard of overfitting, which is common to all prediction problems, is increased by high dimensionality. Secondly, the usual evaluation scheme based on the splitting into learning and test data sets often applies only partially in the case of small sample...